Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disorder characterised by progressive formation and enlargement of fluid-filled cysts in the renal parenchyma, most commonly due to ...

Critical Path Institute (C-Path) is thrilled to announce its Polycystic Kidney Disease Outcomes Consortium (PKDOC) has been awarded an Autosomal Dominant Tubulointerstitial Kidney Disease (ADTKD) ...

A novel UMOD variant classified as likely pathogenic was identified in a 25-year-old man and his affected relatives with ...

New research shows how a mutant form of a protein named STAT3 causes a genetically dominant immunodeficiency. "Accordingly, this study provides vital insight into a signaling pathway essential in ...

A new correspondence explores how falling total fertility rates and disease-specific factors may reduce future new cases of ...

Data from this Australian study showed a higher prevalence of intracranial aneurysms (ICAs) in patients with ADPKD compared with the general population. Many patients in the study had no known risk ...