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Part 2: PT-141 vs Kisspeptin Explained PT-141 and Kisspeptin are often mentioned together, but they work through completely different pathways in the brain. One influences melanocortin receptors involved in sexual motivation, while the other works upstream in the hypothalamic-pituitary-gonadal axis, helping regulate hormone signaling. Understanding the difference between desire signaling and hormone production signaling matters when looking at the physiology behind libido and reproductive hormon
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